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. 2017 Nov 15;36:159. doi: 10.1186/s13046-017-0629-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Overexpression of miR-193a suppresses the formation of prostate xenograft tumors in vivo. a Fluorescence microscope is used for detecting transfection efficiency for LV-miR-193a transfection. b and c Subcutaneous tumors formed in nude mice by PC3 cells with stably overexpression of miR-193a or control at 28 days. d Tumor volume of miR-193a-overexpressiong PC3 cells at indicated time. e Histograms describing the mean tumor weights of each group. f Immunohistochemical staining of Ki-67, CD31, and CD34 in the endpoint tumors. Scale bars represent 50 μm. Each bar represents the mean ± SD of three independent experiments. *P < 0.05