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Effects of sPRR‐His on urinary sPRR excretion, water intake, and urine volume in lithium loaded mice. Male C57/BL6 mice were treated with vehicle, LiCl alone or in combination with sPRR‐His for 14 d. At the end of the experiment, animals were placed in metabolic cages for 24‐h urine collection. (A) ELISA deletion of urinary sPRR excretion (n = 5 mice per group). (B) Water intake (n = 10 mice per group). (C) Urine volume (n = 10 mice per group). Data are mean ± SE.
