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. 2017 Nov 7;18:187. doi: 10.1186/s12931-017-0670-2

Table 2.

Overview of studies in experimental rat CDH

Our group Others
Increased expression of ETA (RNA and protein level) and ETB (RNA level) - Increased expression of ETA and ETB (RNA and protein level) [7]
Increased expression of ECE-1 (RNA level) - Increased expression of ET-1 after 1 and 6 h of ventilation (RNA level) [18]
- Increased response of arterioles to ET-1 [44]
Increased expression of eNOS (RNA and protein level) - Increased expression of eNOS (RNA and protein level) [15]
- Increased expression of eNOS after 1 h of ventilation (RNA level) [18]
- Decreased expression of eNOS (RNA and protein level) [13]
Increased expression of Ptgir (RNA level) and decreased expression of Tbxas1 (RNA level) - Increased levels of prostaglandin I2 and an increased ratio of prostaglandin I2 and thromboxane (protein level) [34]