Lipin proteins associate with membranes of several organelles, including the ER, endolysosomes, mitochondria, and lipid droplets. See text for description of mechanisms. EndoLy: late endosome or lysosome; AutoLyso: autolysosome; AutoPhg: autophagososme; ER: endoplasmic reticulum; Mito: mitochondria; NE: nuclear envelope; Nuage: Nuage pi-body; PA: phosphatidic acid; DAG: diacylglycerol; TAG: triacylglycerol; PDK/Vps34, protein kinase D/phosphatidylinositol-3 kinase; PLD, phospholipase D; MitoPLD, a phospholipase D family member found on mitochondria.