Table 4.
Means ± standard error of the mean (SEM) of percentages for cell viability and apoptosis with Annexin V/ Propidium iodide by flow cytometry in NSCLC cancer cell line after 24h incubation with drugs (representative data).
| Drug combinations | Dead % | Late Apoptotic % | Early Apoptotic % | Live % |
|---|---|---|---|---|
| Untreated cells NSCLC | 0.5±0.6 | 5.5 ±1.4 | 1.8±1 | 92±3.3 |
| Carboplatin | 2±1.1 | 3±1 | 16±2.2 | 79±3 |
| Carboplatin + sildenafil + theophylline + roflumilast | 1±0.8 | 1.5±1 | 12±2 | 86±3.1 |
| Carboplatin + sildenafil | 2.6±1.2 | 3±1.5 | 19±1.7 | 75±2.8 |
| Cisplatin | 0.5±0.8 | 9±1.5 | 3±1.4 | 88±3 |
| Cisplatin + theophylline + roflumilast | 0.5±1.1 | 24±4 | 1±2 | 75±3.5 |