Table 5.
Means ± standard error of the mean (SEM) of percentages for cell viability and apoptosis with Annexin V/ Propidium iodide by flow cytometry in NSCLC cancer cell line after 48h incubation with drugs (representative data).
| Drug combinations | Dead % | Late Apoptotic % | Early Apoptotic % | Live % |
|---|---|---|---|---|
| Untreated cells NSCLC | 0.5±0.6 | 5.5 ±1.4 | 1.8±1 | 92±3.3 |
| Carboplatin | 0.9±1 | 8.9±2 | 7±1.9 | 83±3.1 |
| Carboplatin + sildenafil + theophylline + roflumilast | 1.1±0.5 | 17±1.3 | 6.5±2 | 75±3.3 |
| Carboplatin + sildenafil | 2±1 | 15±2.5 | 7.3±2.3 | 75±2.6 |
| Cisplatin | 0.5±0.9 | 11±2.5 | 10±2.3 | 79±2.5 |
| Cisplatin + theophylline + roflumilast | 0.8±0.9 | 7±1.9 | 2±0.8 | 91±3 |