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. 2017 Oct 17;8(18):3764–3773. doi: 10.7150/jca.20900

Figure 4.

Figure 4

ITGBL1 expression is positively correlated with a KRAS/EMT gene program in GC. A. The mRNA expression of ITGBL1 was increased in invasive subtype of GC compared with the metabolic and proliferative subtypes of GC revealed using the GSE35809 dataset. B-F. Performance of GSEA based on GEO datasets. Patients were divided into low and high groups by the median ITGBL1 expression. High expression of ITGBL1 correlated with the KRAS/EMT signaling pathway revealed using the GSE35809 (B), and GSE13911 (C), GSE15459 (D), GSE34942 (E) and GSE57303 (F) datasets. NES, normalized enrichment score.