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Overexpression of SMOC2 induces G0/G1 phase cell cycle arrest in HCC cells. A, B. Flow cytometric analysis of Annexin V/PI-stained cells. Overexpression of SMOC2 using LV-SMOC2 induced G0/G1 arrest in both HepG2 (A) and Bel-7402 (B) cells. P-values were calculated using the Student's t-test; *P < 0.05, **P < 0.01 and ***P < 0.001 versus negative control LV-NC.
