Fig. 2.

Pharmacological activation of LXR mimics early-pregnancy lipogenesis in mice. A: expression of lipogenic genes. B: expression of cholesterol homeostatic genes. C: total triglycerides and cholesterol measured in lipid extracts. D: total triglycerides and cholesterol measured in mouse serum. Results are represented as means ± SE (n = 6–8); ^aP < 0.05, comparison of nonpregnant T0901317-fed groups [days (D) 7–18] vs. nonpregnant group (D0); ^bP < 0.05, comparison of pregnant T0901317-fed groups (D7-18) vs. pregnant group (D0); ^cP < 0.05, comparison of pregnant T0901317-fed group vs. corresponding nonpregnant T0901317-fed group. P values were determined by one-way ANOVA with Newman-Keuls post hoc testing.