Fig. 3.

LXR is required for lipogenesis during early mouse pregnancy. A: expression of lipogenic genes. B: expression of cholesterol homeostatic genes. C: total cholesterol and triglycerides measured in hepatic lipid extracts. D: total triglycerides and cholesterol measured in mouse serum. ^aP < 0.05, comparison of pregnant wild-type (WT) groups [days (D) 7–18] vs. nonpregnant WT controls (D0); ^bP < 0.05, comparison of pregnant LXR DKO groups (D7–18) vs. nonpregnant LXR DKO controls (D0); ^cP < 0.05, comparison LXR DKO group vs. corresponding WT group. P values were determined by one-way ANOVA with Newman-Keuls post hoc testing.