Table 3.
Univariate and multiple analyses of mortality
| Univariate | Multiple | |||||
|---|---|---|---|---|---|---|
| Variable | B | Exp beta (HR) | P | B | Exp beta (HR) | P |
| sST2 >30 ng/mL | 2.618 | 13.714 | <0.001 | 1.910 | 6.756 | 0.002 |
| Hemoglobin, g/dL | -0.543 | 0.581 | <0.001 | -0.350 | 0.705 | <0.001 |
| Total cholesterol, mg/dL | -0.020 | 0.980 | 0.002 | |||
| Age, years | 0.055 | 1.057 | 0.012 | 0.049 | 1.050 | 0.013 |
| Hypertension | 1.112 | 3.041 | 0.040 | |||
| Atrial fibrillation | 1.067 | 2.906 | 0.047 | |||
| Left atrium size, cm | 1.215 | 3.370 | 0.004 | |||
| Right ventricular dilatation | 0.984 | 2.674 | 0.036 | |||
| Creatinine, mg/dL | 0.833 | 2.300 | 0.020 | |||
| Triglyceride, mg/dL | -0.016 | 0.984 | 0.006 | |||
| HDL cholesterol, mg/dL | -0.060 | 0.942 | 0.015 | -0.067 | 0.936 | 0.010 |
| LDL cholesterol, mg/dL | -0.024 | 0.976 | 0.003 | |||
| Digoxin usage | 1.125 | 3.080 | 0.049 | |||
| Aldosterone antagonist usage | -1.185 | 0.306 | 0.014 | |||
| LV diastolic diameter, cm | 0.331 | 1.392 | 0.278 | |||
| LVEF, % | -0.032 | 0.696 | 0.393 | |||
All the variables from Table 1 were examined, and only those significant at a P<0.1 and those with a correlated sST2 level are shown in univariate analysis. The multiple Cox regression analysis included all univariate predictors and those correlated with sST2 levels. B - beta coefficient; HDL - high density lipoprotein; LDL - low density lipoprotein; LV - left ventricular; LVEF - left ventricular ejection fractions; HR - hazard ratio; Abbreviations in Table 1