Table S1.
Summary of raw data for delta a* and visual MED graded at 24 h, 48 h, and 72 h
| Lesion | Delta a* | Visual |
|---|---|---|
| Subject 1 | ||
| 24 h | ||
| SSR, no ACCS | 5.78 | 2+ |
| SSR, immediate ACCS | 1.17 | Trace |
| SSR, immediate ACCS | 1.38 | Trace |
| SSR, delayed ACCS | 9.34 | 2+ |
| SSR, delayed ACCS | 10.03 | 2+ |
| Visit 4 | ||
| 48 h | ||
| SSR, no ACCS | 2.17 | 1+ |
| SSR, immediate ACCS | Biopsy | Trace |
| SSR, immediate ACCS | 1.44 | Trace |
| SSR, delayed ACCS | 10.37 | 2+ |
| SSR, delayed ACCS | 9.94 | 2+ |
| Visit 5 | ||
| 72 h | ||
| SSR, no ACCS | 3.36 | 1+ |
| SSR, immediate ACCS | Biopsy | Trace |
| SSR, immediate ACCS | 0.77 | tan |
| SSR, delayed ACCS | 4.24 | 2+ |
| SSR, delayed ACCS | 8.55 | 2+ |
| Subject 2 | ||
| 24 h | ||
| SSR, no ACCS | 2.93 | 1+ |
| SSR, immediate ACCS | 0.67 | Trace |
| SSR, immediate ACCS | 5.13 | Trace |
| SSR, delayed ACCS | 8.22 | 2+ |
| SSR, delayed ACCS | 17.44 | 2+ |
| Visit 4 | ||
| 48 h | ||
| SSR, no ACCS | 5.79 | 1+ |
| SSR, immediate ACCS | Biopsy | Trace |
| SSR, immediate ACCS | 4.19 | Trace |
| SSR, delayed ACCS | 6.10 | 2+ |
| SSR, delayed ACCS | 14.37 | 2+ |
| Visit 5 | ||
| 72 h | ||
| SSR, no ACCS | 4.52 | 1+ |
| SSR, immediate ACCS | Biopsy | Trace |
| SSR, immediate ACCS | 1.92 | Trace |
| SSR, delayed ACCS | 7.25 | 2+ |
| SSR, delayed ACCS | 13.34 | 2+ |
| Subject 3 | ||
| 24 h | ||
| SSR, no ACCS | 13.79 | 2+ |
| SSR, immediate ACCS | 5.98 | 1+ |
| SSR, immediate ACCS | 7.17 | 1+ |
| SSR, delayed ACCS | 12.09 | 2+ |
| SSR, delayed ACCS | 16.49 | 2+ |
| Visit 4 | ||
| 48 h | ||
| SSR, no ACCS | 11.80 | 2+ |
| SSR, immediate ACCS | Biopsy | 1+ |
| SSR, immediate ACCS | 3.88 | 1+ |
| SSR, delayed ACCS | 11.05 | 2+ |
| SSR, delayed ACCS | 9.12 | 2+ |
| Visit 5 | ||
| 72 h | ||
| SSR, no ACCS | 7.98 | 2+ |
| SSR, immediate ACCS | Biopsy | 1+ |
| SSR, immediate ACCS | 3.23 | 1+ |
| SSR, delayed ACCS | 7.70 | 2+ |
| SSR, delayed ACCS | 6.51 | 2+ |
| Subject 4 | ||
| 24 h | ||
| SSR, no ACCS | 9.37 | 2+ |
| SSR, immediate ACCS | 2.54 | 1+ |
| SSR, immediate ACCS | 4.10 | 1+ |
| SSR, delayed ACCS | 7.45 | 2+ |
| SSR, delayed ACCS | 8.51 | 2+ |
| Visit 4 | ||
| 48 h | ||
| SSR, no ACCS | 4.64 | 2+ |
| SSR, immediate ACCS | Biopsy | Biopsy |
| SSR, immediate ACCS | 7.44 | 1+ |
| SSR, delayed ACCS | 6.31 | 2+ |
| SSR, delayed ACCS | 6.40 | 2+ |
| Visit 5 | ||
| 72 h | ||
| SSR, no ACCS | 7.17 | 2+ |
| SSR, immediate ACCS | Biopsy | Biopsy |
| SSR, immediate ACCS | 3.98 | 1+ |
| SSR, delayed ACCS | 7.49 | 2+ |
| SSR, delayed ACCS | 8.12 | 2+ |
| Subject 5 | ||
| 24 h | ||
| SSR, no ACCS | 4.59 | 2+ |
| SSR, immediate ACCS | 0.54 | Trace |
| SSR, immediate ACCS | 2.19 | 1+ |
| SSR, delayed ACCS | 5.33 | 2+ |
| SSR, delayed ACCS | 12.99 | 2+ |
| Visit 4 | ||
| 48 h | ||
| SSR, no ACCS | 7.89 | 2+ |
| SSR, immediate ACCS | Biopsy | Trace |
| SSR, immediate ACCS | 2.63 | Trace |
| SSR, delayed ACCS | 5.17 | 2+ |
| SSR, delayed ACCS | 13.84 | 2+ |
| Visit 5 | ||
| 72 h | ||
| SSR, no ACCS | 4.28 | 1+ |
| SSR, immediate ACCS | Biopsy | Trace |
| SSR, immediate ACCS | 1.83 | 1+ |
| SSR, delayed ACCS | 4.72 | 1+ |
| SSR, delayed ACCS | 12.29 | 2+ |
| Subject 6 | ||
| 24 h | ||
| SSR, no ACCS | 7.44 | 2+ |
| SSR, immediate ACCS | 2.42 | 1+ |
| SSR, immediate ACCS | 6.64 | 1+ |
| SSR, delayed ACCS | 17.14 | 2+ |
| SSR, delayed ACCS | 20.33 | 2+ |
| Visit 4 | ||
| 48 h | ||
| SSR, no ACCS | 7.73 | 2+ |
| SSR, immediate ACCS | Biopsy | Trace |
| SSR, immediate ACCS | 3.79 | 1+ |
| SSR, delayed ACCS | 12.98 | 2+ |
| SSR, delayed ACCS | 19.98 | 2+ |
| Visit 5 | ||
| 72 h | ||
| SSR, no ACCS | 3.33 | Trace |
| SSR, immediate ACCS | Biopsy | Trace |
| SSR, immediate ACCS | 5.60 | 1+ |
| SSR, delayed ACCS | 16.74 | 2+ |
| SSR, delayed ACCS | 11.57 | 2+ |
| Subject 7 | ||
| 24 h | ||
| SSR, no ACCS | 18.48 | 2+ |
| SSR, immediate ACCS | 11.63 | 2+ |
| SSR, immediate ACCS | 8.77 | 2+ |
| SSR, delayed ACCS | 18.19 | 2+ |
| SSR, delayed ACCS | 20.52 | 2+ |
| Visit 4 | ||
| 48 h | ||
| SSR, no ACCS | 16.57 | 1+ |
| SSR, immediate ACCS | Biopsy | biopsy |
| SSR, immediate ACCS | 8.85 | 1+ |
| SSR, delayed ACCS | 14.66 | 2+ |
| SSR, delayed ACCS | 18.24 | 2+ |
| Visit 5 | ||
| 72 h | ||
| SSR, no ACCS | 11.75 | 2+ |
| SSR, immediate ACCS | Biopsy | 1+ |
| SSR, immediate ACCS | 7.32 | 1+ |
| SSR, delayed ACCS | 15.67 | 2+ |
| SSR, delayed ACCS | 17.87 | 2+ |
| Subject 8 | ||
| 24 h | ||
| SSR, no ACCS | 16.34 | 2+ |
| SSR, immediate ACCS | 3.65 | Trace |
| SSR, immediate ACCS | 2.17 | Trace |
| SSR, delayed ACCS | 12.32 | 2+ |
| SSR, delayed ACCS | 17.25 | 2+ |
| Visit 4 | ||
| 48 h | ||
| SSR, no ACCS | 16.65 | 2+ |
| SSR, immediate ACCS | Biopsy | Trace |
| SSR, immediate ACCS | 1.73 | Trace |
| SSR, delayed ACCS | 11.91 | 2+ |
| SSR, delayed ACCS | 16.08 | 2+ |
| Visit 5 | ||
| 72 h | ||
| SSR, no ACCS | 16.78 | 2+ |
| SSR, immediate ACCS | Biopsy | Trace |
| SSR, immediate ACCS | 1.78 | Trace |
| SSR, delayed ACCS | 10.27 | 2+ |
| SSR, delayed ACCS | 13.32 | 2+ |
| Subject 9 | ||
| 24 h | ||
| SSR, no ACCS | 13.40 | 2+ |
| SSR, immediate ACCS | 1.93 | Trace |
| SSR, immediate ACCS | 2.46 | Trace |
| SSR, delayed ACCS | 16.40 | 2+ |
| SSR, delayed ACCS | 19.41 | 2+ |
| Visit 4 | ||
| 48 h | ||
| SSR, no ACCS | 13.04 | 2+ |
| SSR, immediate ACCS | Biopsy | Biopsy |
| SSR, immediate ACCS | −0.31 | Trace |
| SSR, delayed ACCS | 16.60 | 2+ |
| SSR, delayed ACCS | 21.36 | 2+ |
| Visit 5 | ||
| 72 h | ||
| SSR, no ACCS | 9.94 | 2+ |
| SSR, immediate ACCS | Biopsy | biopsy |
| SSR, immediate ACCS | 1.96 | Trace |
| SSR, delayed ACCS | 14.08 | 2+ |
| SSR, delayed ACCS | 21.11 | 2+ |
| Subject 10 | ||
| 24 h | ||
| SSR, no ACCS | 7.77 | 2+ |
| SSR, immediate ACCS | 2.31 | Trace |
| SSR, immediate ACCS | 1.93 | Trace |
| SSR, delayed ACCS | 8.03 | 2+ |
| SSR, delayed ACCS | 12.69 | 2+ |
| Visit 4 | ||
| 48 h | ||
| SSR, no ACCS | 9.93 | 2+ |
| SSR, immediate ACCS | Biopsy | Biopsy |
| SSR, immediate ACCS | 1.98 | 2+ |
| SSR, delayed ACCS | 9.75 | 2+ |
| SSR, delayed ACCS | 7.66 | 2+ |
| Visit 5 | ||
| 72 h | ||
| SSR, no ACCS | 6.48 | 1+ |
| SSR, immediate ACCS | Biopsy | biopsy |
| SSR, immediate ACCS | 1.35 | Trace |
| SSR, delayed ACCS | 5.59 | 1+ |
| SSR, delayed ACCS | 6.27 | 1+ |
Note: Skin that could not be evaluated due to biopsies was noted with “Biopsy”.
Abbreviations: ACCS, amnion-derived cellular cytokine solution; MED, mean erythema dose; SSR, simulated solar radiation.