Table 3.
Mean Values for AUC, AUC60, Cmax, and tmax for Both Types of CSII Catheters on Days 1, 3, and 5
Catheter type | Day | ![]() |
![]() |
![]() |
![]() |
---|---|---|---|---|---|
CC (n = 5a swine) | 1 | 82.7 ± 37.6 | 50.9 ± 12.9 | 90.7 ± 26.8 | 35.0 ± 17.3 |
3 | 63.1 ± 22.8 | 47.0 ± 25.6 | 73.9 ± 41.0 | 20.0 ± 12.2 | |
5 | 71.1 ± 29.4 | 54.9 ± 20.8 | 114.7 ± 30.1 | 12.0 ± 4.5 | |
IC (n = 6 swine) | 1 | 68.5 ± 36.0 | 44.3 ± 23.2 | 120.0 ± 59.3 | 43.3 ± 28.8 |
3 | 63.1 ± 51.8 | 42.7 ± 40.0 | 115.0 ± 86.2 | 20.0 ± 6.3 | |
5 | 40.1 ± 37.6 | 29.0 ± 31.3 | 105.1 ± 87.7 | 33.3 ± 18.6 |
Data are provided as mean ± SD.
PK from swine 1 excluded due to incomplete insertion of CC1 catheter.
AUC, areas under the curve; PK, pharmacokinetics.