Table 2.
Anticipated power on secondary outcomes
| Variables | Instrument | Subscales | Cronbach’s alpha | Hypothesized Difference/ SD (anticipated power) |
|---|---|---|---|---|
| Muscle strength and endurance legs | 30 s sit-to-stand test | Total numbers of repetitions | NR (not reported) | 2.0/2.5 (0.99) |
| Symptoms | COPD Assessment Test (CAT) | Eight symptom questions (0–5 points) Total score 0–40 points |
0.88 | 3.0/5.5 (0.88) |
| Disease specific quality of life | Clinical COPD Questionnaire (CCQ) | Ten items, three domain score (symptoms, functional and mental) and overall score. Items score ranges from 0 to 6 |
Overall score 0.91 Symptom score 0.78 Functional score 0.89 Mental score 0.80 |
Overall score 0.4/1.1 (0.55) |
| Anxiety and depression | Hospital Anxiety and Depressions Scale (HADS) | HADS-A scale (0–21) HADS-D scale (0–21) |
HADS-A 0.83 HADS-D 0.82 |
HADS-A 1.5/2.5 (0.93) HADS-D 1.5/2.5 (0.93) |
| Health-Related Quality of Life | EuroQol 5-Dimension Questionnaire (EQ-5D) | EQ5D-questionnaire (mobility, self-care, usual activities, pain/discomfort, and anxiety/depression) Norm based utility score (−0.624–1.000) EQ5D-VAS (0–100 mm) |
Not relevant – only one question in each dimension | EQ5D-VAS 8/16 (0.82) |
| Physical activity |
activePAL™ activity monitor (PAL Technologies Ltd., Glasgow, UK) |
Steps per day Minutes lying/sitting Minutes standing/walking Number of body transitions per day |
NR (not reported) | Steps per day 1100/2262 (0.50) |