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. Author manuscript; available in PMC: 2017 Nov 16.
Published in final edited form as: Gynecol Oncol. 2016 Oct 15;143(3):674–683. doi: 10.1016/j.ygyno.2016.10.005

Fig. 1.

Fig. 1

Alterations in adipocytokine expression patterns in obesity and EOC. Green arrows indicate upregulation and red arrows indicate downregulation. Black arrow indicates cytokine recruitment of cells to the tumor microenvironment. Blue arrows with a circular end indicate that the cytokine increases the primary process indicated by the green arrow. NK cell – natural killer cell; IFN-γ – interferon gamma; IGF-1 – insulin-like growth factor 1; IGF-1 R – insulin-like growth factor 1 receptor; TNF-α – tumor necrosis factor alpha; TAM – tumor associated macrophage; HIF – hypoxia inducible factor; IL-6 – interleukin 6; VEGF – vascular endothelial growth factor; OB-Rb – Leptin receptor; EOC – epithelial ovarian cancer.