Fig. 1.

Schematic Representation of a possible mechanism of mtH₂O₂ processing enacted by the interaction of SOD2 and GPx-1. Catalase which is often referred to as a major H₂O₂ scavenger throughout the cells is actually confined to peroxisomes and more likely acts as a buffer preventing oxidative damage when H₂O₂ are high enough to force H₂O₂ diffusion into peroxisomes. The Figure also depicts some alternative mechanisms that often contribute to the elevation of H₂O₂ production rates in most cells. ETC stands for Electron Transport Chain.