a. IDH mutant gliomas with 1p/19q co-deletions |
Case |
Age, sex |
WHO |
Location |
Recurrent pattern |
PFS (mo) |
OS (mo) |
F/U (mo) |
CNAs |
W1-1 |
43M |
O Gr3 |
Bi frontal |
- |
44 |
64 |
(dead) |
−1p, +1q12−32.1, −1q32.2-ter, +11, +17, +19p, −19q |
W1-2 |
49M |
HGG |
Bi frontal |
1 |
|
|
|
−1p, −15q13-22.3, −19q |
W2-1 |
34M |
O Gr2 |
Lt frontal |
- |
63 |
(alive) |
65 |
−1p, −14, −19q |
W2-2 |
39M |
O Gr3 |
Lt frontal |
1 |
|
|
|
−1p, −14q, −19q, +21q |
W3-1 |
53M |
O Gr2 |
Lt frontal |
- |
104 |
(alive) |
134 |
−1p, +7, −15q, −19q, +22q |
W3-2 |
64M |
O Gr3 |
Lt frontal ∼ parietal |
2 |
|
|
|
−1p, +2, +7, −9p, +9q, −15q, −19q |
W4-1 |
35F |
O Gr2 |
Rt frontal |
- |
52 |
(alive) |
120 |
FF−1p, −19q |
W4-2 |
40F |
O Gr3 |
Rt frontal |
1 |
|
|
|
NA |
W5-1 |
24M |
O Gr2 |
Lt temporal |
- |
69 |
121 |
(dead) |
−1p, −19q |
W5-2 |
32M |
O Gr3 |
Lt temporal ∼ insula |
2 |
|
|
|
−1p, −4, +7q21.3-ter, +8, +11, −14q22-23, −18, −19q |
W5-3 |
33M |
O Gr3 |
Lt temporal, insula, occipital |
2 |
|
|
|
−1p, +3, −4, +5, +7, +9q, +10p, −10q, −13q, −15q11.2-22.3, +15q22.2-ter, −19q |
W5-4 |
34M |
O Gr3 |
Lt temporal, insula, frontal, occipital |
2 |
|
|
|
−1p, −4, −10q, −13q, −14q, −15qcen-21, +15q24-ter, −19q |
W6-1 |
40F |
O Gr3 |
Lt frontal |
- |
105 |
(alive) |
133 |
−1p, +1q, +3, −9, +12q14, −15q, +17, +18, −19q, +20 |
W6-2 |
49F |
not clear |
Lt frontal |
1 |
|
|
|
NA |
W7-1 |
57M |
O Gr2 |
Lt temporal |
- |
33 |
87 |
(dead) |
−1p, −14q13-24, −19q |
W7-2 |
63M |
O Gr3 |
Lt temporal ∼ parietal |
2 |
|
|
|
−1p, +7, −14q21-24.3, −15q15-22.1, −19q |
W7-3 |
64M |
O Gr3 |
Lt temporal ∼ parietal |
2 |
|
|
|
−1p, +7, −14q21-24.3, −15q15-22.1, −19q |
W8-1 |
41M |
A Gr3 |
Lt frontal |
- |
3 |
76 |
(dead) |
NA |
W8-2 |
45M |
O Gr3 |
Lt frontal, temporal, rt frontal |
2 |
|
|
|
−1p, +7q, +8, +18p, −18q, −19q, +22q |
W9-1 |
29M |
O Gr3 |
Lt frontal |
- |
49 |
(alive) |
88 |
−1p, −19q |
W9-2 |
34M |
O Gr3 |
Lt frontal |
1 |
|
|
|
−1p, −19q |
W10-1 |
33M |
OA Gr2 |
Lt temporal |
- |
25 |
(alive) |
52 |
−1p, +2p, −9p, −19q |
W10-2 |
36M |
O Gr3 |
Lt temporal |
1 |
|
|
|
−1p, −17p, −18q, −19q |
W10-3 |
38M |
O Gr2 |
Lt temporal ∼ parietal |
2 |
|
|
|
NA |
W11-1 |
36F |
O Gr3 |
Lt frontal |
- |
17 |
(alive) |
49 |
−1p, −19q |
W11-2 |
37F |
O Gr3 |
Lt frontal |
1 |
|
|
|
−1p, +1q, −2, +6, +7, +8, −9, +11, −16, +17, −18, +19p, −19q, +21, −22 |
W12-1 |
38F |
O Gr2 |
Lt frontal |
- |
16 |
(alive) |
32 |
−1p, −19q |
W12-2 |
39F |
|
Lt frontal ∼ rt frontal |
2 |
|
|
|
NA |
W13-1 |
44M |
O Gr3 |
Lt frontal |
- |
15 |
(alive) |
29 |
−1p, −19q |
W13-2 |
45M |
|
Lt frontal |
1 |
|
|
|
NA |