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. 2017 Sep 13;8(49):84928–84944. doi: 10.18632/oncotarget.20863

Figure 2. BxPC3 derived Exo expand myeloid derived suppressor cells.

Figure 2

Monocytes, dendritic cells, granulocytic and monocytic derived suppressor cells (gMDSCs and mMDSCs) were counted after PBMCs were incubated for four days with complete, Exo free and Exo enriched BxPC3 (dark grey columns) or BxPC3-SMAD4+ (light grey columns) conditioned media (CM). PBMCs were always run in parallel in complete, Exo free and Exo enriched non-conditioned medium (NC, black columns). All data are given as the average values ± SEM obtained from eight donors * = p<0.05 with respect to NC and # = p<0.05 with respect to NC and BxPC3 (Tukey’s multiple comparisons test).