Table 4. Primer sequences used for real-time PCR analysis.

Genes	Primer sequence
Ki67	Forward	5’- GGCACTTTCTGTGAGGAGGAC-3’
	Reverse	5’-GCAGTCAGGCGTGTTGTTCT-3’
PCNA	Forward	5’- ATTCTGGAAATGACAGTGAAGCAC-3’
	Reverse	5’-CACCTCGGTATTAACGCCCTC-3’
Bax	Forward	5’-GAAGCCGGTGGTGGAGAA-3’
	Reverse	5’-GCTTGGAGTTGGGCTGGTG-3’
Bcl-2	Forward	5’- GAAGCAGGTAATGGAGCAAGGA-3’
	Reverse	5’-GAAGCGTAGTTGTTGAGATGCG-3’
Caspase-3	Forward	5’-GCGGTTGTAGAAGTTAATAAAGGTA-3’
	Reverse	5’-CATGGCACAAAGCGACTGG-3’
Caspase-9	Forward	5’-TGCTCAGACCAGAGATTCGC-3’
	Reverse	5’-TCTTTCTGCTCGACATCACCAA-3’
VEGF	Forward	5’-ACTTTGGTATCGTGGAAGGACTCAT-3’
	Reverse	5’-GTTTTTCTAGACGGCAGGTCAGG-3’
MMP-2	Forward	5’-GAGTGCATGAACCAACCAGC-3’
	Reverse	5’-AAACTTGCAGGGCTGTCCTT-3’
MMP-9	Forward	5’-TCTATGGTCCTCGCCCTGAA-3’
	Reverse	5’-TTGTATCCGGCAAACTGGCT-3’
Notch1	Forward	5’-GGCACTTTCTGTGAGGAGGAC-3’
	Reverse	5’-GCAGTCAGGCGTGTTGTTCT-3’
Hes1	Forward	5’-CAGATCAATGCCATGACCTACC-3’
	Reverse	5’-AGCCTCCAAACACCTTAGCC-3’
Hes5	Forward	5’-AGCCCCAAAGAGAAAAACCGACTG-3’
	Reverse	5’-TGGAGCGTCAGGAACTGCACGG-3’
Hey-L	Forward	5’-ACCGCATCAACAGTAGCCTTTCT-3’
	Reverse	5’-GCATTTTCAAGTGATCCACCGTC-3’
GAPDH	Forward	5’-ACTTTGGTATCGTGGAAGGACTCAT-3’
	Reverse	5’-GTTTTTCTAGACGGCAGGTCAGG-3’