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. 2017 Jul 28;8(49):85252–85262. doi: 10.18632/oncotarget.19654

Figure 6. The effects of F2 on expression of MMP-2 and migration and invasion of U87 cells.

Figure 6

(A) Western blot analysis of MMP-2 levels in extracts of U87 cells incubated under normoxic or hypoxic conditions with the indicated concentrations of F2. (B) Western blot analysis of MMP-2 levels in cells transfected with HIF-1α or control siRNA incubated under hypoxia for 16 h. (C) Migration and invasion assays were done as described in the Methods section. Values are means ± SEM of three experiments. ### P<0.001 compared with normoxic group; ** P<0.01 and ***P<0.001 compared with hypoxic group.