Table 1. Associations between clinical patient characteristics at diagnosis and IL-31 plasma levels in HL patients.
| Variable | Number |
IL-31 level median (pg/ml) |
P | ||
|---|---|---|---|---|---|
| IPS parameters |
Age, years (n=109) |
< 45 >45 |
75 34 |
10 14 |
0.9 |
|
Gender (n=109) |
Female Male |
53 56 |
15 5 |
0.4 | |
|
Stage (n=109) |
I-III IV |
80 29 |
5 83 |
0.1 | |
|
White blood cell count (n=108) |
≤ 15 x 103/ml > 15 x 103/ml |
89 19 |
5 294 |
0.01 | |
|
Lymphocyte count (n=105) |
≥ 600/ml < 600/ml |
93 12 |
7 18 |
0.4 | |
|
Hemoglobin level (n=108) |
≥ 10.5 g/dl < 10.5 g/dl |
89 19 |
7 25 |
0.2 | |
|
Albumin level (n=105) |
≥ 40 g/l < 40 g/l |
55 50 |
5 21 |
0.1 | |
|
IPS (n=106) |
0-2 3-5 |
72 34 |
5 182 |
0.002 | |
|
Histology subtype (n=109) |
cHL Nodular sclerosis cHL Mixed cellularity cHL lymphocyte rich cHL NOS NLPHL |
86 1 4 15 3 |
15 7 9 13 15 |
0.5 | |
|
B-symptoms (n=109) |
Absent Present |
68 41 |
5 22 |
0.2 |