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. 2017 Jul 12;8(49):85276–85289. doi: 10.18632/oncotarget.19205

Figure 3. MiR-200b-3p and miR-429-5p suppressed the mobility of TNBC cells.

Figure 3

(A) Representative images for wound healing assessments. (B) Representative images from Transwell assays (migration and invasion) showing that transfection with miR-200b-3p and miR-429-5p mimics suppressed the migration and invasion ability of MDA-MB-231 TNBC cells (100 fold). Quantification of data is shown as bar graphs. (C) Representative Western blots showing that transfection with miR-200b-3p and miR-429-5p suppressed expression of MMP2 and MMP9 in both MDA-MB-231 and HCC1937 TNBC cells. Quantification of data is shown as bar graphs. NC, negative control. Three independent experiments were performed. Numbers of invading cells or gray scale images of each assay were counted or scanned and presented as a bar chart in which the vertical axis is the mean ± SD. ** indicates statistical differences at p < 0.01 and *** indicates statistical differences at p < 0.001.