Table 2. The RNA in the multi-RNA-based classifier significantly associated with survival of CRC patients in training set.
| Symbol | Chromosome location | Type | Univariate Cox regression analysis | LASSO coefficient | ||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | ||||
| Protective RNAs | ||||||
| MMP1 | 11q22.3 | mRNA | 0.854 | 0.784-0.932 | 0.001 | -0.068643 |
| MS4A1 | 11q12 | mRNA | 0.869 | 0.799-0.945 | 0.001 | -0.030945 |
| IZUMO2 | 19q13.33 | mRNA | 0.897 | 0.822-0.945 | 0.014 | -0.024213 |
| GIF | 11q13 | mRNA | 0.881 | 0.806-0.961 | 0.005 | -0.014259 |
| Risky RNAs | ||||||
| FAM132B | 2q37.3 | mRNA | 1.140 | 1.001-1.297 | 0.048 | 0.003712 |
| CPB1 | 3q24 | mRNA | 1.110 | 1.019-1.207 | 0.016 | 0.007147 |
| NXPH4 | 12q13.3 | mRNA | 1.108 | 1.023-1.200 | 0.012 | 0.008292 |
| OSR1 | 2p24.1 | mRNA | 1.172 | 1.048-1.312 | 0.005 | 0.014616 |
| PCOLCE2 | 3q21-q24 | mRNA | 1.135 | 1.038-1.240 | 0.005 | 0.025477 |
| RNF112 | 17p11.2 | mRNA | 1.276 | 1.082-1.495 | 0.003 | 0.035002 |
| TNNT2 | 1q32 | mRNA | 1.236 | 1.089-1.410 | 0.002 | 0.045565 |
| GABRD | 1p36.3 | mRNA | 1.315 | 1.096-1.577 | 0.003 | 0.046474 |
| MIR27A | 19p13.13 | miRNA | 1.191 | 1.035-1.370 | 0.015 | 0.016724 |
| HOTAIR | 12q13.13 | lncRNA | 1.112 | 1.027-1.203 | 0.008 | 0.004548 |
HR, hazard ratio; CI, confidential interval.