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. 2017 Aug 12;8(49):85516–85525. doi: 10.18632/oncotarget.20231

Figure 2. Time-coursed treatment efficacy of TEM, rMETase and their combination in the BRAF V600E mutant melanoma.

Figure 2

Line graphs show relative tumor volume at each time point relative to the initial tumor volume. All treatments significantly inhibited tumor growth compared to untreated control (TEM: p=0.0081; rMETase: p=0.0037; TEM-rMETase: p=0.0024). In addition, TEM and rMET combination therapy was significantly more efficacious than either TEM (p=0.0051) or rMETase (p=0.0051) alone at day 14. There was no significantly difference between TEM and rMETase. **p < 0.01. Error bars: ± SD.