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. 2017 Aug 18;8(49):85584–85598. doi: 10.18632/oncotarget.20337

Figure 5. HCV Core activates DNMT1 expression in the presence of ATRA via activation of AP-1.

Figure 5

HepG2-vector and HepG2-Core cells were either mock-treated or treated with ATRA for 48 h in the presence or absence of SP600125. (A) Levels of the indicated proteins were measured by western blotting. (B) The DNA methylation pattern of p14 promoter was analyzed by MSP as in Figure 4C. To present the ratio of methylated p14 to unmethylated p14 in the corresponding sample, DNA bands were quantified with the use of ImageJ image processing and analysis software (NIH). (C) Levels of the indicated proteins were measured by western blotting.