. 2017 Aug 24;8(49):85716–85748. doi: 10.18632/oncotarget.20464

Table 1. miRNA expression in the lung of 10-week old A/J mice of both genders, as related to exposure to ECS since birth and/or administration of aspirin after weaning.

miRNA	Treatment of mice				Main regulated functions
miRNA	Sham	Aspirin	ECS	ECS + Aspirin	Main regulated functions
miR-16	0.18	1.32^a	1.00^a	1.26^a	Apoptosis
miR-133	0.77	0.14^a	0.97	0.11^a,b	Inflammation
miR-137	0.49	1.20^a	0.77^a	1.65^a,b	Cell proliferation, COX-2 negative regulator
miR-191	0.89	1.08	0.43^a	1.04^b	COX regulation, Cell proliferation
miR-199b	0.94	1.04	1.72	0.86^b	COX activation
miR-223	1.08	1.05	0.51^a	1.02	Stress response, Protein repair, k-Ras regulation
miR-543	1.17	0.27^a	1.85	1.14	Stress response, Inflammation

The results are expressed in FU (Fluorescence Units).

Statistical analysis: ^aP < 0.05 compared with Sham; ^bP < 0.05 compared with ECS-exposed mice in the absence of chemopreventive agents.