Figure 7. Polysaccharides extracted from H. erinaceus improved the pathological parameters of the TNBS-induced mice.
(A) Body weight changes; (B) levels of LPS in serum; (C) levels of cytokines GM-CSF, TNF-γ, IL-10, IL-12, IL-17α, IL-4, TNF-α, and VGEF-α in serum; (D) histopathological changes in the colon; and (E) histopathological changes in the spleen. Control is the normal without any treatments; model (Mice were induced by TNB), model and high-dose antibiotics, polysaccharides [100 mg/(kg · d)], Bifidobacterium, polysaccharides plus high-dose antibiotics, polysaccharides plus Bifidobacterium, Bifidobacterium plus high-dose antibiotics, and polysaccharides plus Bifidobacterium plus high-dose antibiotics.