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. 2017 Sep 23;8(49):86435–86446. doi: 10.18632/oncotarget.21199

Table 3-1. Stratified analysis for the association between rs3742330 and GC clinical characteristics.

Clinical characteristics Genotype OR (95% C.I.)* P Allele OR (95% C.I.) P
AA AG GG A G
Tumor size
 <5 cm 100 86 21 1.00 (Reference) 286 128 1.00 (Reference)
 5-10 cm 83 94 27 0.73 (0.49-1.11) 0.120 260 148 0.79 (0.58-1.06) 0.104
 ≥10 cm 26 26 4 0.93 (0.49-1.75) 0.803 78 34 1.03 (0.64-1.66) 0.909
Tumor stages
 1a 29 30 5 1.00 (Reference) 88 40 1.00 (Reference)
 1b 14 18 4 0.77 (0.31-1.91) 0.533 46 26 0.80 (0.42-1.55) 0.483
 2a 13 18 10 0.56 (0.23-1.37) 0.165 44 38 0.53 (0.28-0.97) 0.027
 2b 38 29 5 1.35 (0.65-2.81) 0.385 74 39 0.86 (0.49-1.53) 0.590
 3a 25 24 6 1.01 (0.46-2.21) 0.988 74 36 0.93 (0.52-1.67) 0.807
 3b 29 32 10 0.83 (0.40-1.75) 0.601 90 52 0.79 (0.46-1.35) 0.353
 3c 46 51 12 0.88 (0.45-1.72) 0.690 143 75 0.87 (0.53-1.42) 0.548
 4 79 80 21 0.94 (0.51-1.74) 0.844 238 122 0.89 (0.56-1.40) 0.586
Degree of differentiation
 Low 187 198 47 1.00 (Reference) 572 292 1.00 (Reference)
 Medium 82 82 21 1.04 (0.73-1.50) 0.812 246 124 1.01 (0.78-1.32) 0.923
 High 4 4 2 12 8
Lymphatic metastasis
 0 66 72 13 1.00 (Reference) 204 98 1.00 (Reference)
 1 42 42 19 0.89 (0.52-1.52) 0.643 126 80 0.76 (0.51-1.11) 0.139
 2 49 51 9 1.05 (0.62-1.78) 0.842 149 69 1.04 (0.70-1.53) 0.847
 3a 62 50 12 1.29 (0.78-2.13) 0.298 174 74 1.13 (0.77-1.65) 0.511
 3b 19 33 9 0.58 (0.30-1.14) 0.091 71 51 0.67 (0.42-1.06) 0.068