Table 3-1. Stratified analysis for the association between rs3742330 and GC clinical characteristics.
Clinical characteristics | Genotype | OR (95% C.I.)* | P | Allele | OR (95% C.I.) | P | |||
---|---|---|---|---|---|---|---|---|---|
AA | AG | GG | A | G | |||||
Tumor size | |||||||||
<5 cm | 100 | 86 | 21 | 1.00 (Reference) | 286 | 128 | 1.00 (Reference) | ||
5-10 cm | 83 | 94 | 27 | 0.73 (0.49-1.11) | 0.120 | 260 | 148 | 0.79 (0.58-1.06) | 0.104 |
≥10 cm | 26 | 26 | 4 | 0.93 (0.49-1.75) | 0.803 | 78 | 34 | 1.03 (0.64-1.66) | 0.909 |
Tumor stages | |||||||||
1a | 29 | 30 | 5 | 1.00 (Reference) | 88 | 40 | 1.00 (Reference) | ||
1b | 14 | 18 | 4 | 0.77 (0.31-1.91) | 0.533 | 46 | 26 | 0.80 (0.42-1.55) | 0.483 |
2a | 13 | 18 | 10 | 0.56 (0.23-1.37) | 0.165 | 44 | 38 | 0.53 (0.28-0.97) | 0.027 |
2b | 38 | 29 | 5 | 1.35 (0.65-2.81) | 0.385 | 74 | 39 | 0.86 (0.49-1.53) | 0.590 |
3a | 25 | 24 | 6 | 1.01 (0.46-2.21) | 0.988 | 74 | 36 | 0.93 (0.52-1.67) | 0.807 |
3b | 29 | 32 | 10 | 0.83 (0.40-1.75) | 0.601 | 90 | 52 | 0.79 (0.46-1.35) | 0.353 |
3c | 46 | 51 | 12 | 0.88 (0.45-1.72) | 0.690 | 143 | 75 | 0.87 (0.53-1.42) | 0.548 |
4 | 79 | 80 | 21 | 0.94 (0.51-1.74) | 0.844 | 238 | 122 | 0.89 (0.56-1.40) | 0.586 |
Degree of differentiation | |||||||||
Low | 187 | 198 | 47 | 1.00 (Reference) | 572 | 292 | 1.00 (Reference) | ||
Medium | 82 | 82 | 21 | 1.04 (0.73-1.50) | 0.812 | 246 | 124 | 1.01 (0.78-1.32) | 0.923 |
High | 4 | 4 | 2 | 12 | 8 | ||||
Lymphatic metastasis | |||||||||
0 | 66 | 72 | 13 | 1.00 (Reference) | 204 | 98 | 1.00 (Reference) | ||
1 | 42 | 42 | 19 | 0.89 (0.52-1.52) | 0.643 | 126 | 80 | 0.76 (0.51-1.11) | 0.139 |
2 | 49 | 51 | 9 | 1.05 (0.62-1.78) | 0.842 | 149 | 69 | 1.04 (0.70-1.53) | 0.847 |
3a | 62 | 50 | 12 | 1.29 (0.78-2.13) | 0.298 | 174 | 74 | 1.13 (0.77-1.65) | 0.511 |
3b | 19 | 33 | 9 | 0.58 (0.30-1.14) | 0.091 | 71 | 51 | 0.67 (0.42-1.06) | 0.068 |