Table 3-3. Stratified analysis for the association between rs10719 and GC clinical characteristics.
| Clinical characteristics | Genotype | OR (95% C.I.)* | P | Allele | OR (95% C.I.) | P | |||
|---|---|---|---|---|---|---|---|---|---|
| TT | CT | CC | T | C | |||||
| Tumor size | |||||||||
| <5 cm | 106 | 83 | 18 | 1.00 (Reference) | 295 | 119 | 1.00 (Reference) | ||
| 5-10 cm | 104 | 79 | 21 | 0.99 (0.66-1.49) | 0.963 | 287 | 121 | 0.96 (0.70-1.31) | 0.773 |
| ≥10 cm | 30 | 21 | 5 | 1.10 (0.58-2.07) | 0.753 | 81 | 31 | 1.05 (0.65-1.73) | 0.825 |
| Tumor stages | |||||||||
| 1a | 26 | 32 | 6 | 1.00 (Reference) | 84 | 44 | 1.00 (Reference) | ||
| 1b | 20 | 14 | 2 | 1.83 (0.74-4.54) | 0.150 | 54 | 18 | 1.57 (0.79-3.16) | 0.169 |
| 2a | 23 | 14 | 4 | 1.87 (0.78-4.47) | 0.121 | 60 | 22 | 1.43 (0.74-2.75) | 0.251 |
| 2b | 34 | 33 | 5 | 1.31 (0.63-2.74) | 0.439 | 101 | 43 | 1.23 (0.72-2.12) | 0.426 |
| 3a | 30 | 19 | 6 | 1.75 (0.79-3.88) | 0.129 | 79 | 31 | 1.33 (0.74-2.41) | 0.305 |
| 3b | 37 | 24 | 10 | 1.59 (0.76-3.34) | 0.182 | 98 | 44 | 1.17 (0.68-2.00) | 0.553 |
| 3c | 59 | 41 | 9 | 1.72 (0.88-3.38) | 0.086 | 159 | 59 | 1.41 (0.86-2.32) | 0.151 |
| 4 | 85 | 80 | 15 | 1.31 (0.73-2.43) | 0.363 | 250 | 110 | 1.19 (0.76-1.87) | 0.425 |
| Degree of differentiation | |||||||||
| Low | 215 | 179 | 39 | 1.00 (Reference) | 609 | 257 | 1.00 (Reference) | ||
| Medium | 94 | 74 | 17 | 1.05 (0.73-1.50) | 0.792 | 262 | 108 | 1.02 (0.73-1.35) | 0.863 |
| High | 5 | 4 | 1 | 14 | 6 | ||||
| Lymphatic metastasis | |||||||||
| 0 | 69 | 69 | 13 | 1.00 (Reference) | 207 | 95 | 1.00 (Reference) | ||
| 1 | 55 | 39 | 9 | 1.36 (0.80-2.32) | 0.228 | 149 | 57 | 1.20 (0.80-1.81) | 0.360 |
| 2 | 60 | 39 | 10 | 1.46 (0.86-2.46) | 0.137 | 159 | 59 | 1.24 (0.83-1.85) | 0.279 |
| 3a | 67 | 46 | 11 | 1.40 (0.80-2.42) | 0.169 | 180 | 68 | 1.21 (0.83-1.79) | 0.302 |
| 3b | 26 | 26 | 9 | 0.88 (0.46-1.68) | 0.684 | 78 | 44 | 0.81 (0.51-1.44) | 0.360 |