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. 2017 Sep 23;8(49):86576–86591. doi: 10.18632/oncotarget.21245

Figure 3. Immune responses to plasmids containing CpG ODNs in CIK cells.

Figure 3

The mRNA expressions of CiTLR9 (A), CiRIG-I (B), CiIL-2 (C), CiIFNγ2 (D), CiNFκB1 (E) and CiNFκB2 (F) were measured at 0, 24 and 48 h post-infection. CIK cells were stimulated with PBS (control) or plasmids containing CpG ODNs and infected with GCRV. The EF1α gene was used as an internal control to normalize the cDNA template. mRNA levels of the target gene were normalized to those in CIK cells at 0 h. The p value was calculated by student's t-test between experimental and control groups at each time point (*, p ≤ 0.05, **, p ≤ 0.01). Error bars indicate SE (n=3).