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. 2017 Sep 30;8(49):86693–86709. doi: 10.18632/oncotarget.21411

Figure 1. Anti-tumor effects of LNT and cell cycle analysis in MCF-7 cells in vitro.

Figure 1

(A) Cell viability of human normal cells of HBL-100, LO2 and 293T after treatment with LNT for 48 h determined by MTT assay. (B) Cell viability of different human breast cancer cells after treatment with LNT for 72 h determined by MTT assay. (C, D) Cell proliferation of MCF-7 and HBL-100 cells measured by trypan blue dye-exclusion assay, respectively. ap < 0.05 and bp <0.001 versus the control (PBS) at the respective incubation time point. (E) Cell cycle arrest induced by LNT. MCF-7 cells were incubated with LNT at 0, 50, 100 and 200 μg/mL for 24 h, and cell cycle distribution was determined by using the flow cytometry.