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. 2017 Sep 30;8(49):86726–86735. doi: 10.18632/oncotarget.21418

Figure 2. Necroptosis in TNBS-induced colitis.

Figure 2

(A) Immunofluorescence of colonic tissues stained with cleaved caspase-3 (red), TUNEL (green) and DAPI (blue). The enlarged image shows green fluorescence representing TUNEL-positive and caspase-3-negative necroptotic cells and yellow fluorescence representing TUNEL-positive and caspase-3-positive apoptotic cells. (B) Western blot analysis of p-RIPK3. p-RIPK3 is increased in TNBS-induced colitis. *P<0.05 compared with the control group. TNBS, 2,4,6-trinitrobenzenesulfonic acid; p-RIPK3, Phosphorylated receptor-interacting protein kinase 3.