Table 5. Single loci associations with high altitude polycythemia risk in Han subjects.
SNP_ID | Model | Ref Allele | Alt Allele | OR | 95% CI | p value |
---|---|---|---|---|---|---|
rs17676773 | Dominant | G | A | 0.145 | 0.037-0.569 | 0.006 |
Recessive | 0.563 | 0.357-1.576 | 0.264 | |||
Additive | 0.343 | 0.112-1.047 | 0.060 | |||
rs145810451 | Dominant | A | G | 0.107 | 0.019-0.607 | 0.012 |
Recessive | 0.262 | 0.174-0.776 | 0.263 | |||
Additive | 0.229 | 0.055-0.949 | 0.042 | |||
rs17335043 | Dominant | A | C | 0.089 | 0.020-0.405 | 0.002 |
Recessive | 0.473 | 0.169-0.837 | 0.362 | |||
Additive | 0.248 | 0.034-0.525 | 0.007 |
OR: odds ratio; 95% CI: 95% confidence interval; p<0.05 indicates statistical significance for genetic model.