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. 2017 Sep 30;8(49):86769–86783. doi: 10.18632/oncotarget.21423

Figure 2. Oncolytic reovirus induces CXCL10 expression.

Figure 2

(A) Affymetrix expression arrays revealed a significant increase in CXCL10 in mutant RAS HT-1080 cells and WT RAS SK-LMS-1 cells after 48 h treatment with 30 PFU/cell Reolysin. (B-C) qRT-PCR analysis of CXCL10 and CXCL11. Cells were treated with 30 PFU/cell Reolysin for 48 h and then harvested for analysis. Levels of mRNAs were standardized to the expression of GAPDH. Mean ± SD, n = 3, *Indicates a significant difference from the controls, p < 0.05.