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. 2017 Jun 15;6(8):1710–1722. doi: 10.1002/sctm.17-0035

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© 2017 The Authors Stem Cells Translational Medicine published by Wiley Periodicals, Inc. on behalf of AlphaMed Press

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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ASC tracking in FCGS affected cats vs. a control cat. Right lateral scintigraphic images obtained 1 hour post radiolabeled mesenchymal stem cells (MSC) injection in a control cat (A) and an feline chronic gingivostomatitis (FCGS) affected cat (B). Most of the radioactive signal was present within the lungs, likely due to trapping of the MSCs in the capillary bed. Marked radioactive uptake is also present in the kidneys and bladder, likely due to the presence of dissociated label. Additionally, the affected cat appears to have higher radioactive uptake in the region of the oral cavity as compared to the control cat. Focal radioactive uptake is also present in the area of the injected cephalic vein in the FCGS affected cat. The only uptake associated with the thoracic limb in the control cat is within the catheter and injection port. Line graph (C) demonstrates the ratio head/whole body at the different time points for all four cats.