Table 1. Demographic details of TB progressor and control participants.
Participants and sample numbers available for each analysis are also shown.
| Progressors (n = 44) |
Controls (n = 106) |
Total (n = 150) |
|
|---|---|---|---|
| Demographics | |||
| Ethnicity, n (%) | |||
| Coloured (Cape mixed ancestry) | 40 (90.9%) | 97 (91.5%) | 137 (91.3%) |
| Black African | 4 (9.1%) | 9 (8.5%) | 13 (8.7%) |
| Female, n (%) | 32 (73%) | 69 (65%) | 101 (67.3%) |
| Mean age at baseline, years (range) | 15.5 (12–18) | 15.6 (13–18) | 15.6 (12–18) |
| Prior episode of TB, n (%) | 5 (11.4%) | 16 (15.1%) | 21 (14%) |
| RNA-Seq Transcriptomic Analysis | |||
| Participants, n | 38 | 104 | 142 |
| Samples, n | 76 | 243 | 319 |
| Proteomic Analysis | |||
| Participants, n | 36 | 104 | 70 |
| Samples, n | 82 | 290 | 372 |
| Flow Cytometry Analysis | |||
| Participants, n | 33 | 71 | 104 |
| Samples, n | 101 | 133 | 234 |