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(a) Plots of Vmax—μV in the realizations from Fig 10D containing the most extreme DADs out of 106 trials. Curves correspond to the baseline model (blue), 50% reduction of IK1 (red), and both 50% IK1 and 50% ggap (magenta). (b) Spatiotemporal JRyR profiles in each realization from panel (a). Brackets and dotted lines mark the location of the filter window centered on the extreme DAD.
