Table 3. Genotype distribution of HSP70 SNPs.
SNP | First author (year) | Case | Control | HWE | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
AA | AB | BB | Total | AA | AB | BB | Total | X2 | P | ||
rs1043618 | Li (2017) | 124 | 117 | 45 | 286 | 130 | 125 | 31 | 286 | 0.01352 | 0.907435 |
(G> C) | Chang (2011) | 8 | 18 | 1 | 27 | 153 | 139 | 30 | 322 | 0.037921 | 0.845602 |
Konings (2009, Swedish) | 31 | 51 | 11 | 93 | 49 | 44 | 7 | 100 | 0.468949 | 0.493471 | |
Konings (2009, Polish) | 44 | 58 | 14 | 116 | 46 | 58 | 12 | 116 | 0.009615 | 0.92189 | |
Yang (2009) | 37 | 43 | 13 | 93 | 35 | 48 | 18 | 101 | 0.047963 | 0.826647 | |
rs2075800 | Li (2017) | 128 | 128 | 30 | 286 | 112 | 132 | 42 | 286 | 0.093721 | 0.759499 |
(C > T) | Chang (2011) | 10 | 15 | 2 | 27 | 113 | 166 | 43 | 322 | 2.175678 | 0.140208 |
rs2227956 | Li (2017) | 204 | 64 | 8 | 276 | 201 | 73 | 2 | 276 | 2.856668 | 0.090996 |
(A > G) | Konings (2009, Swedish) | 64 | 27 | 0 | 91 | 54 | 39 | 5 | 98 | 0.367347 | 0.544454 |
Konings (2009, Polish) | 95 | 22 | 1 | 118 | 81 | 32 | 4 | 117 | 0.143747 | 0.704584 | |
Yang (2009) | 58 | 34 | 1 | 93 | 67 | 32 | 2 | 101 | 0.673503 | 0.411833 | |
rs2763979 | Li (2017) | 104 | 133 | 49 | 286 | 116 | 139 | 31 | 286 | 1.253581 | 0.26287 |
(C > T) | Chang (2011) | 18 | 9 | 0 | 27 | 179 | 124 | 19 | 322 | 0.165829 | 0.683846 |
rs1061581 | Konings (2009, Swedish) | 24 | 55 | 13 | 92 | 44 | 45 | 11 | 100 | 0.009975 | 0.920442 |
(A > G) | Konings (2009, Polish) | 37 | 61 | 18 | 116 | 43 | 56 | 15 | 114 | 0.236309 | 0.626885 |
Yang (2009) | 43 | 41 | 9 | 93 | 50 | 48 | 3 | 101 | 4.591447 | 0.032132# |
HWE: Hardy-Weinberg equilibrium.
# P < 0.05, showing statistically significant difference.