Table 4.
The comparison of normal liver dosimetric parameters in patients with RILD and without RILD among week1, week2, and week3
| Parameter | Refb | Ptsa with RILD (n = 7) | Pts without RILD (n = 16) | P * [Link] | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Week1 | Week2 | Week3 | Week1 | Week2 | Week3 | Week1 | Week2 | Week3 | ||
| V20 c (%) | NA | 40.9 (32.6–44.1) | 45.6 (36.1–48.9) | 48.8 (40.0–51.9) | 29.9 (19.7–36.6) | 33.1 (22.9–41.2) | 36.4 (25.5–44.3) | 0.521 | 0.010 | 0.227 |
| V30 (%) | NA | 29.7 (23.2–34.8) | 33.8 (27.1–38.2) | 36.5 (30.1–42.3) | 21.9 (10.8–26.1) | 24.7 (13.4–28.6) | 28.2 (16.5–31.8) | 0.111 | 0.008 | 0.503 |
| V40 (%) | NA | 24.1 (16.6–28.3) | 26.9 (21.3–31.2) | 31.0 (24.2–35.9) | 16.4 (7.5–21.5) | 18.6 (9.6–22.2) | 21.1 (11.6–24.2) | 0.025 | 0.074 | 0.002 |
| D50 d (Gy) | 35 | 26.4 (22.3–31.5) | 30.6 (27.3–33.1) | 35.3 (31.8–38.1) | 14.6 (4.5–24.8) | 17.3 (6.7–25.4) | 20.4 (8.1–30.2) | 0.754 | 0.003 | 0.002 |
| Dmean (Gy) | 28 | 25.8 (23.5–27.3) | 28.4 (24.9–32.3) | 32.4 (28.6–36.1) | 18.1 (6.7–25.3) | 21.2 (8.4–27.6) | 24.6 (11.3–31.4) | 0.403 | 0.020 | 0.107 |
a
Pts = patients.
b
Ref = hepatic radiation tolerance.
c
V20 = percentage of the normal liver volume that received exceeding 20Gy in the total normal liver; V30, V40 express the resembling meaning, except for the suffix numbers, which represent the doses received in increments of 10 Gy.
d
D50 = dose to 50% of the normal liver.
*Significance in independent sample t‐test with P value less than 0.05 from two‐sided tests.