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. 2017 Jan 24;18(2):9–14. doi: 10.1002/acm2.12038

Table 2.

Dosimetric comparison (OAR sparing) of 30 patients that were planned by: PRO using the manual objectives as in the clinical plans (clinical); PO using the RapidPlan‐generated objectives (PO); and PRO using the RapidPlan‐generated objectives (PRO). Dose unit (Gy)

Mean SD 95% Confidence interval P
Lower Upper
D50%_FH Clinical 15.10 2.28 14.25 15.95 <0.01
PO 10.16 2.65 9.18 11.15 0.06
PRO 10.43 2.95 9.33 11.53
Dmean_FH Clinical 16.27 2.10 15.49 17.05 <0.01
PO 12.31 1.71 11.67 12.95 <0.01
PRO 12.56 1.87 11.86 13.25
D50%_UB Clinical 28.05 2.60 27.08 29.02 <0.01a
PO 19.18 1.96 18.45 19.91 <0.01
PRO 20.23 2.05 19.47 21.00
Dmean_UB Clinical 29.21 2.10 28.42 29.99 <0.01
PO 22.35 2.02 21.59 23.10 <0.01
PRO 23.12 2.09 22.34 23.90
V107% Clinical 0.04 0.11 0.00 0.08 0.01a
PO Not observed 0.32a
PRO 0.01 0.05 ‐0.01 0.03

Wilcoxon signed‐rank test (abnormal distribution); otherwise paired samples t‐test (normal distribution).

a

SD, standard deviation; D50%, dose to the 50% volume of the structure; Dmean, mean dose; FH, femoral head, UB, urinary bladder, and V107%, volume receiving over 107% of the prescribed dose.