Segmentation of inhomogeneous targets (MR): (a) the glioma in T2 MR image (case 8), (b) T1c MR image (case 9), and (c) the glioma and edema in FLAIR MR image (case 10). The ROIs, which are indicated by the yellow boxes, are shown in the zoomed‐in views for clarity. First column: SPs labeled inside (green) and outside (red) of the targets on one transversal slice of T2 ((a)), T1c ((b)), and FLAIR ((c)) MR image. Second column: segmentation by RW. Third column: segmentation by GC. Fourth column: segmentation by SPARSE. In the second, third, and fourth columns, the red and green masks represent the calculated and the ground truth segmentations, respectively, and the images are rendered in 3D.