Table 1.
Average ± SE (mL) | |||||||||
Treatment | Dose | ||||||||
1 h | % | 2 h | % | 3 h | % | 4 h | % | ||
(p.o.) | (mg/Kg) | ||||||||
Control | - | 1.33 ± 0.06 | - | 1.60 ± 0.14 | - | 1.69 ± 0.12 | - | 1.7 ± 0.12 | - |
Indomethacin | 10 | 0.82 ± 0.02a | 38.6 | 0.88 ± 0.02a | 45.0 | 0.97 ± 0.06a | 42.5 | 1.0 ± 0.07a | 41.3 |
AE | 200 | 1.13 ± 0.06a | 15.6 | 1.33 ± 0.06a | 16.7 | 1.47 ± 0.05a | 12.7 | 1.46 ± 0.05a | 14.0 |
AE | 400 | 1.2 ± 0.04 | 9.8 | 1.5 ± 0.07 | 6.7 | 1.65 ± 0.08 | 2.3 | 1.61 ± 0.08 | 5.4 |
%, edema inhibition percentage (n = 8/group). SE, average standard error. ap < 0.05 compared to control (Anova, followed by Tukey).