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. 2017 Nov 16;12(11):e0188121. doi: 10.1371/journal.pone.0188121

Fig 10. SPHK2 knockdown reduces apoptosis in the other three serotypes of DENV.

Fig 10

Huh7 cells were reverse transfected with siSPHK2 or siNTC for 24 hours and then infected with different serotypes of DENV at MOI 10 for 48 hours. Caspase activity was measured and is represented individually for (A) DENV1-; (B) DENV3-; and, (C) DENV4-infected Huh7 cells. The results are represented in relative luminescent unit (RLU). The results are expressed as the average of three independent experiments ± SD. The asterisks indicate statistically significant differences between groups (p < 0.05) (Student’s t test).