Table 4.

Doses to esophagus, heart, and spinal cord from the full KBM and the four sub‐KBMs divided by tumor location validated on the full and partial validation sets

	Validation Set	Esophagus		Heart		Spinal Cord
Model		0.035 cc	5 cc	0.035 cc	15 cc	0.035 cc	0.35 cc	1.2 cc
Full KBM	Full	$10.3\pm 5.5$	$5.4\pm 3.7$	$13.3\pm 9.9$	$7.6\pm 5.6$	$8.4\pm 3.3$	$7.8\pm 2.9$	$7.1\pm 2.5$
${\text{KBM}}_{\mathrm{C}}$	Full	$10.2\pm 5.5$	$5.4\pm 3.8$	$13.0\pm 9.6$	$7.4\pm 5.4$	$8.4\pm 3.3$	$7.8\pm 2.9$	$7.1\pm 2.6$
${\text{KBM}}_{\mathrm{P}}$	Full	$10.0\pm 5.3$ a	$5.1\pm 3.5$ a	$13.1\pm 9.6$	$7.3\pm 5.6$	$8.3\pm 3.4$	$7.7\pm 3.0$	$6.9\pm 2.6$
${\text{KBM}}_{\text{ANT}}$	Full	$10.6\pm 5.8$ b	$5.2\pm 3.6$	$13.4\pm 9.9$	$7.7\pm 5.7$ b	$8.2\pm 3.3$ a , b	$7.6\pm 2.9$ a , b	$6.8\pm 2.6$ a , b
${\text{KBM}}_{\text{POST}}$	Full	$10.2\pm 5.4$ b	$5.3\pm 3.8$	$13.0\pm 9.6$	$7.3\pm 5.4$ b	$8.6\pm 3.2$ b	$8.0\pm 2.9$ b	$7.3\pm 2.6$ a , b
Full KBM	Central	$14.0\pm 5.0$	$8.0\pm 2.5$	$17.8\pm 9.8$	$9.5\pm 5.8$	$10.4\pm 3.0$	$9.5\pm 2.6$	$8.6\pm 2.3$
${\text{KBM}}_{\mathrm{C}}$	Central	$13.9\pm 5.3$	$8.1\pm 2.8$	$17.3\pm 8.9$	$9.2\pm 5.6$	$10.4\pm 3.1$	$9.6\pm 2.8$	$8.7\pm 2.5$
${\text{KBM}}_{\mathrm{P}}$	Central	$13.6\pm 4.8$	$7.4\pm 2.6$ a	$17.1\pm 8.3$	$8.9\pm 5.3$	$10.4\pm 3.1$	$9.4\pm 2.6$	$8.4\pm 2.4$
Full KBM	Peripheral	$7.9\pm 14.0$	$3.7\pm 3.4$	$9.8\pm 9.3$	$6.1\pm 5.1$	$7.1\pm 2.8$	$6.6\pm 2.5$	$6.0\pm 2.2$
${\text{KBM}}_{\mathrm{C}}$	Peripheral	$7.7\pm 18.9$	$3.6\pm 3.3$	$9.7\pm 9.0$	$6.0\pm 5.1$	$7.1\pm 2.7$	$6.6\pm 2.4$	$6.0\pm 2.2$
${\text{KBM}}_{\mathrm{P}}$	Peripheral	$7.6\pm 4.1$	$3.5\pm 3.1$	$10.0\pm 9.5$	$6.1\pm 5.3$	$7.0\pm 2.8$	$6.5\pm 2.6$	$5.9\pm 2.3$
Full KBM	Anterior	$6.1\pm 2.8$	$2.9\pm 2.2$	$12.3\pm 12.0$	$7.2\pm 6.6$	$6.0\pm 2.0$	$5.7\pm 1.8$	$5.3\pm 1.6$
${\text{KBM}}_{\text{ANT}}$	Anterior	$6.1\pm 2.6$	$2.8\pm 2.8$	$12.7\pm 12.1$	$7.2\pm 6.6$	$5.7\pm 1.9$ b	$5.5\pm 1.7$ a , b	$5.1\pm 1.5$ a , b
${\text{KBM}}_{\text{POST}}$	Anterior	$5.9\pm 2.4$	$2.5\pm 1.9$	$11.4\pm 11.1$	$6.5\pm 6.0$	$6.2\pm 2.0$ a , b	$6.0\pm 1.9$ a , b	$5.6\pm 1.8$ a , b
Full KBM	Posterior	$12.8\pm 5.3$	$6.8\pm 3.7$	$13.8\pm 9.1$	$7.8\pm 9.1$	$9.8\pm 3.1$	$8.9\pm 2.8$	$8.0\pm 2.5$
${\text{KBM}}_{\text{ANT}}$	Posterior	$13.2\pm 5.6$ b	$6.6\pm 3.5$	$13.9\pm 13.8$	$8.0\pm 5.4$	$9.6\pm 3.1$	$8.7\pm 2.7$	$7.8\pm 2.5$
${\text{KBM}}_{\text{POST}}$	Posterior	$12.6\pm 5.1$ b	$6.9\pm 3.7$	$13.8\pm 9.1$	$7.7\pm 5.2$	$9.9\pm 3.0$	$9.1\pm 2.7$	$8.2\pm 2.5$

^aIndicates a statistically significant difference between the studied model and the full KBM model.

^bIndicates a statistically significant difference between the studied model and the complementary model.