Table 3. White matter microstructure measures in non-hypertensive and hypertensive groups after propensity score matching.
Non-hypertensive | Hypertensive | p value | |
---|---|---|---|
N | 1559 | 1559 | |
White matter microstructure measure | |||
FA | 0.041±0.613 | –0.043±0.653 | 0.001 |
MD | –0.070±0.616 | 0.063±0.680 | <0.001 |
MO | 0.000±0.341 | –0.006±0.353 | 1.000 |
ICVF | 0.036±0.788 | –0.042±0.836 | 0.046 |
OD | 0.013±0.483 | –0.014±0.497 | 0.706 |
ISOVF | –0.071±0.510 | 0.059±0.580 | <0.001 |
Brain volume measure | |||
Total brain volume (ml) | 1506.4±71.0 | 1506.7±70.9 | 1.000 |
Grey matter volume (ml) | 796.8±45.8 | 795.8±44.4 | 1.000 |
White matter volume (ml) | 709.6±40.7 | 710.8±41.5 | 1.000 |
Variables were expressed as means ± standard deviations and were analyzed using the Student’s t-test. White matter microstructural measures are expressed as mean z-scores referenced to the total study population (n = 4659). Significance levels were set at p<0.05 after Bonferroni correction. Abbreviations: FA, Fractional anisotropy; ICVF, Intracellular volume fraction; ISOVF, Isotropic volume fraction; MD, Mean diffusivity; MO, Diffusion tensor mode; OD, Orientation dispersion.