Table 5. White matter microstructure measures in normotensive and pre-hypertensive groups after propensity score matching.
| Non-hypertensive | Hypertensive | p value | |
|---|---|---|---|
| N | 694 | 694 | |
| White matter microstructure measure | |||
| FA | 0.048±0.586 | 0.029±0.604 | 1.000 |
| MD | –0.171±0.579 | –0.127±0.591 | 0.949 |
| MO | –0.033±0.337 | –0.033±0.331 | 1.000 |
| ICVF | 0.066±0.751 | 0.072±0.762 | 1.000 |
| OD | 0.093±0.473 | 0.103±0.495 | 1.000 |
| ISOVF | –0.178±0.479 | –0.097±0.517 | 0.015 |
| Brain volume measure | |||
| Total brain volume (ml) | 1531.2±72.4 | 1526.9±71.6 | 0.774 |
| Grey matter volume (ml) | 817.5±45.3 | 815.8±45.7 | 1.000 |
| White matter volume (ml) | 713.8±40.5 | 711.1±39.9 | 0.629 |
Variables were expressed as means ± standard deviations and were analyzed using the Student’s t-test. White matter microstructural measures are expressed as mean z-scores referenced to the total study population (n = 4659). Significance levels were set at p<0.05 after Bonferroni correction. Abbreviations: FA, Fractional anisotropy; ICVF, Intracellular volume fraction; ISOVF, Isotropic volume fraction; MD, Mean diffusivity; MO, Diffusion tensor mode; OD, Orientation dispersion.