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. 2017 Nov 16;12(11):e0187333. doi: 10.1371/journal.pone.0187333

Fig 2. Endogenous IL-10 drives the influence of B-1 lymphocytes in B16F10 behavior.

Fig 2

A) The deficiency in IL-10 production did not affect the phenotype and the number of B-1 lymphocytes recovered from the culture of peritoneal cavity cells; B) but affected their ability to increase the metastatic potential of B16F10 melanoma cells. Bars represent the mean number of lung colonies per experimental condition ±SD. **p <0.001, using one-way ANOVA with Tukey’s post hoc test.