Table 1. Significant PRCCs for initial protein concentration parameters.
Output | [Varied Input Parameter] PRCC Value |
|||
---|---|---|---|---|
CAC1 | [CaM] 0.9509 |
[AC1] 0.9204 |
[CaMKII] -0.8177 |
|
CAC8-Ct | [CaM] 0.9498 |
[AC8-Ct] 0.9209 |
[Ng] -0.8752 |
[CaMKII] -0.5186 |
CAC8-Nt | [CaM] 0.9567 |
[AC8-Nt] 0.9116 |
[Ng] -0.7441 |
|
CCaN | [CaM] 0.9564 |
[CaN] 0.9442 |
[CaMKII] -0.8999 |
|
CCaMKII | [CaM] 0.9766 |
[CaMKII] 0.9177 |
[AC8-Nt] -0.6657 |
|
CMLCK | [CaM] 0.9381 |
[MLCK] 0.934 |
[CaMKII] -0.7392 |
[Ng] -0.6167 |
CNg | [CaM] 0.9759 |
[Ng] 0.8827 |
||
CNOS | [NOS] 0.996 |
[CaM] 0.8076 |
[Ng] -0.7238 |
Enumeration of Partial Rank Correlation Coefficient (PRCC) values for variations in initial protein concentrations that most strongly affect each average CaM-bound protein concentration, Cb, for simulations with Ca2+ frequency of 10 Hz. Only inputs with absolute PRCC values greater than 0.5 are shown.