Table 1. Profiling of steroids in the male and female mouse brain at postnatal day 10.
| Steroids | Males | Females | Detection limit |
|---|---|---|---|
| (pg/g) | (pg/g) | (pg/g or pg/ml) | |
| Testosterone | 173 ± 26*** | 64 ± 17 | 1 |
| 5α-Dihydrotestosterone | 9 ± 2 | 8 ± 2 | 2 |
| Androstanediol | 21 ± 3 | 19 ± 3 | 1 |
| Androstenedione | 66 ± 16 | 60 ± 14 | 2 |
| Estradiol | 5 ± 1.6* | 1.5 ± 0.7 | 1 |
| 5α-Androstanedione | 27 ± 3 | 19 ± 3 | 2 |
| Pregnenolone | 4812 ± 229 | 5543 ± 390 | 2 |
| 20α-dihydropregnenolone | 192 ± 15 | 148 ± 30 | 1 |
| Progesterone | 56 ± 9 | 106 ± 41 | 20 |
| 5α-Dihydroprogesterone | 670 ± 101 | 563 ±154 | 5 |
| 3β,5α-Tetrahydroprogesterone | 6.1 ± 1.2 | 6.6 ± 2.2 | 0.5 |
| 20α-Dihydroprogesterone | 205 ± 82 | 155 ± 46 | 10 |
| Deoxycorticosterone | 430 ± 100 | 716 ± 263 | 5 |
| 3α,5α-Tetrahydro deoxycorticosterone | 18 ± 6 | 13 ± 3 | 2 |
| Corticosterone | 8295 ± 1519 | 9191 ± 2239 | 20 |
Profiling of steroids by gas chromatography coupled to tandem mass spectrometry (GC-MS/MS). Results are presented as means ± SEM (7< n > 19).
***p < 0.001;
*p = 0.05