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. 2017 Nov 6;13(11):e1005827. doi: 10.1371/journal.pcbi.1005827

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© 2017 Sloma, Mathews

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 5 — Prediction of non-canonical base pairs by predicting the conserved structure with multiple homologous sequences for (A) an MVE virus nuclease resistant RNA, (B) a D. radiodurans SRP hairpin domain, and (C) a O. sativa Twister ribozyme. Prediction accuracy is shown for structures composed of highly probable pairs using information from a single sequence (blue) or a TurboFold calculation on 10 sequences (red). In panels A and B, no blue line is present because the single sequence prediction did not correctly predict any pairs. Also shown is prediction using evolutionary couplings from the plmc program [16] (green).